ISSN 1302-9940 | e-ISSN 1308-8491

Hzl Arama




The Journal of the Child Grup B Meningokok Enfeksiyonlar ve Alama [J Child]
J Child. 2019; 19(3): 116-123 | DOI: 10.5222/j.child.2019.06926

Grup B Meningokok Enfeksiyonlar ve Alama

zge Kaba, Ayper Somer
stanbul niversitesi Tp Fakltesi, ocuk Sal ve Hastalklar Anabilim Dal, ocuk Enfeksiyon Hastalklar Bilim Dal, stanbul

Dnyann heryerinde endemi ve epidemilere neden olan meningokokal enfeksiyonlar, saatler ierisinde mortalite ile sonulanan tablolara yol aabilir. Corafi zellikler, konak faktr, mikroorganimann serogrubu gibi faktrler seyri etkilemektedir. Edinilen srveyans verilerine gre epidemilere en sk neden olan serogruplar A, B, C, W135 ve Y olarak belirlenmitir. Bunun zerine gelitirilen A, C, W135 ve Y serogruplarn ieren yeni meningokok alar ile tm dnyada bu serogruplarn grlme oran belirgin olarak azalma gstermitir. lkemizde ise baklama programnn Hib ve pnmokok alarnn eklenmesiyle zenginletirilmesinden sonra meningokokal hastalklar arpc bir ekilde kendini gstermitir. n planda olduu grlen serogrup Bye kar korunmann yollar aranm ve son dnemde ters vaksinoloji yntemiyle serogrup B as(4CMenB) gelitirilmitir.

Anahtar Kelimeler: Meningokok B, invazif meningokokal hastalk, ocukluk a, alama

Group B Meningococcal Infections and Vaccination

zge Kaba, Ayper Somer
Division of Paediatric Infectious Disease, Department of Pediatrics, Istanbul University, Istanbul, Turkey

Meningococcal infections leading to endemics and epidemics all over the world can lead to mortality resulting in hours. Factors such as geographical characteristics, host factors, serogroup of microorganism affect the course. According to the surveillance data, serogroups A, B, C, W135 and Y were the most common causes of epidemics. With the new meningococcal vaccines including serogroups A, C, W135 and Y, the incidence of these serogroups decreased significantly all over the world. In our country, meningococcal diseases have been striking after the immunization program has been enriched with the addition of Hib and pneumococcal vaccines. Protection against serogroup B, which appears to be in the forefront, has been sought and recently, serogroup B vaccine (4CMenB) has been developed by reverse vaccination method.

Keywords: Meningococcus B, invazive meningococcal disease, childhood, vaccination

zge Kaba, Ayper Somer. Group B Meningococcal Infections and Vaccination. J Child. 2019; 19(3): 116-123

Sorumlu Yazar: zge Kaba, Trkiye
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